99% Effective: First Hormone-Free Male Birth Control Pill Enters Human Trials
YCT-529, a hormone-free male birth control pill, has shown high effectiveness in animals and is now in human trials, marking a breakthrough in male contraception.
While the FDA has approved more than 20 types of contraceptives, only two options currently exist for men: condoms and vasectomies. Although about 25% of women who use contraception rely on the oral birth control pill, there is no equivalent pill available for men.
However, research from the University of Minnesota College of Pharmacy, published in Communications Medicine, has paved the way for the first hormone-free male birth control pill to reach clinical trials.
This new drug, YCT-529, is an innovative, hormone-free, orally administered contraceptive designed for men. Developed in partnership with DOI: 10.1038/s43856-025-00752-7
The research was supported by the Share.
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