The battle for overall wireless headphone supremacy is fiercely contested every year, but when it comes to banishing undesirable noise, Bose usually comes out on top. That was certainly the case when we pitted 2025’s contenders for your cash against each other, and Bose’s QuietComfort Ultra took away the title of best noise-canceling headphones. And right now, the very same headphones are $100 off for Prime Day at $329.

Note that this deal applies to the previous generation QuietComfort Ultra, rather than the refreshed second-gen model Bose has just announced. These offer improved battery life, ANC and audio performance, and they also support lossless audio over a wired USB-C connection for the first time. However, these headphones also cost $449 out of the gate, which is considerably more than the heavily slashed price of their predecessor.

If you don’t have to have the latest and greatest in every product line, the first-gen QuietComfort Ultra will be more than enough for the vast majority of people. They still offer exceptional noise-canceling, very good sound and a comfortable design. Bose’s “Immersive Audio” spatial sound feature can be a bit hit and miss, but with the right content it can be incredible. And while $329 is still a lot of money, $100 is a big saving on what were very recently the best Bose headphones you can buy.

Click here for our rolling coverage of the best Prime Day 2025 deals, which we’ll be updating as the event rolls on.